Melanoma arising in a giant nevus spilus maculosus

Synchronous melanomas arising within nevus spilus*

Nevus spilus is a melanocytic cutaneous lesion consisting of a light brown background macule with numerous superimposed darker maculopapular speckles. Melanoma arising from a nevus spilus is rare, with less than 40 cases reported to date. The absolute risk for malignant transformation is not well defined, lacking a standardized management approach. We report a new case of melanoma arising from ...

Large congenital nevus spilus—improved follow-up through the use of in vivo reflectance confocal microscopy

BACKGROUND Nevus spilus (NS) is a potential precursor of melanoma; the vast majority of cases reported in the literature were histologically classified as superficial spreading melanoma. OBJECTIVE To demonstrate the diagnostic value of reflectance confocal microscopy (RCM) in this subtype of congenital nevi. METHODS We report a case of a large congenital NS with equivocal clinical and dermo...

In situ malignant melanoma on nevus spilus in an elderly patient.

Nevus spilus is the term usually given to a pigmented skin lesion, congenital or acquired, that may occur anywhere on the body, consisting of a large light tan patch with numerous superimposed darker scattered maculae or papulae that are flat or slightly raised. For a long time, nevus spilus was believed to be a benign lesion. However, in 1957 Perkinson reported a melanoma appearing on nevus sp...

Treatment of nevus spilus with CO2 Laser

Background: Nevus spilus can produce considerable disfigurement. There is no specific and successful treatment for this nevus. Objective: The purpose of this study was to evaluate the efficacy of CO2 laser in the treatment of nevus spilus. Patients and Methods: This quasi-experimental clinical trial was performed on 47 patients with spilus nevus in Al-Zahra Hospital in Isfahan. The diagnosis of...

Nevus Spilus: A Review of the Literature